我国联合培养博士生的演进、向度与展望——基于巴斯德象限的视角     

刘贤伟  高飞  邹洋 《中国高教研究》2021,(1):89-95

《教育规划纲要》颁布实施以来,我国博士生教育中的联合培养实践进入了快速发展的时期。科技政策领域的巴斯德象限模型为解释我国联合培养博士生工作的相关政策和发展动向提供了一个逻辑框架,从巴斯德象限模型的视角出发,对《教育规划纲要》实施十年以来我国国家层面推动的高校与(工程)科研院所联合培养博士生项目、协同创新中心项目、博士专业学位联合培养等实践开展及相关政策进行梳理总结,进一步提出我国联合培养博士生体系的象限模型,并据此分析我国联合培养博士生体系的核心向度与未来发展方向。  相似文献   

地质超前预报系统在栋梁坡隧道施工中的应用     

刘倩  檀朝彬  韩星  吕会喜  展先彪 《实验室研究与探索》2021,(2):43-48

基于地震反射波法超前预测系统的原理及主要技术手段,以栋梁坡隧道工程为实例,针对隧道复杂的地质条件,施工过程中将超前地质预报和地质素描调查相结合,先对隧道全段范围内地形、地层岩性等进行全面核查,然后结合核查结果运用地震反射波法预报掌子面前方的节理裂隙发育情况,围岩完整性等地质信息。开挖后验证情况与预测结果基本一致,为后续预防突水塌方等隧道地质灾害事故的发生提供数据支撑,有效保证栋梁坡隧道的施工安全。  相似文献   

免疫细胞分离鉴定综合实验设计     

孔小丽  陈思  陈玮琳  黄钟 《实验室研究与探索》2021,(1)

在传统免疫细胞分离检测实验教学的基础上,利用高性能正置荧光显微镜和流式细胞仪以不同技术检测鉴定免疫细胞,对实验教学内容和教学方法进行了改革和实践。将教学与临床科研相结合,利用大型贵重仪器以及合理安排实验时间开发综合实验。结果表明,学生不仅可以更有效消化医学免疫学课程基础知识,了解学科新技术的发展,而且可以培养学生的科研创新能力和综合分析能力。  相似文献   

晋绥抗日根据地农业研究     

王明前 《苏州教育学院学报》2021,(1)

晋绥边区党和政府把农业作为战时经济的主体重点加以经营,在恢复正常生产的基础上,进一步挖掘农业生产潜力。边区党和政府积极鼓励垦荒事业,专门制定法令进行政策扶持,通过经济杠杆作用奖励发动民间力量兴办水利事业。同时,帮助农民提高农业生产技术,奖励某些特产的种植,增加农业的综合效益。畜牧业也得到大力扶持。边区粮政是农业生产成就的具体实现,也是边区财政制度的重要组成。边区党和政府严格执行粮食财政的预决算制度,规范粮食的支出程序,逐步完善粮食财政制度,并采取政府赈济和民间借粮相结合的办法,调剂粮食资源。  相似文献   

What emotional-centred challenges do children attending special schools face over primary–secondary school transition?     

Charlotte L. Bagnall  Claire L. Fox  Yvonne Skipper 《Journal of Research in Special Educational Needs》2021,21(2):156-167

Primary–secondary school transition encompasses multiple social, academic and environmental changes which can negatively impact children’s emotional well-being. Children with Social, Emotional and Mental Health difficulties (SEMH) are believed to be especially vulnerable during this time. However, the voices of children with SEMH are heavily underrepresented in this field within practice and research. The present case study examined how children with SEMH difficulties within one special school experience primary–secondary school transition and how they are supported, in order to make recommendations to improve this period. The case study was qualitative and longitudinal, conducted over 18-months and methodologies included ethnographic observations, child photo-elicitation focus groups (with 11 Year 6 children) and three adult interviews. Findings demonstrated that over primary–secondary school transition children with SEMH difficulties (a) negotiate significant structural changes in support (often unanticipated) and (b) need to feel a sense of safety and belonging. To manage this effectively, transition provision for children with SEMH difficulties needs to consider their short-term emotional well-being whilst still in primary school, in addition to their long-term well-being looking ahead to secondary school. Greater collaboration and communication across schools and stakeholders can help ensure children receive continuity in standards and support.  相似文献   

技能竞赛对高职学生创业能力影响的因素研究     

许波 《宁波职业技术学院学报》2021,(2):27-32

技能竞赛是培养高职学生创业能力的重要途径,技能竞赛可以分为创业竞赛和职业能力竞赛。通过对河源职业技术学院的183份有效样本数据进行因子分析,筛选出三个主因子,分别从专业能力、管理能力和成长潜力维度对高职学生创业能力产生影响,然后以创业竞赛和职业技能竞赛为自变量对三个主因子进行回归分析。研究发现创业竞赛对专业能力和管理能力有显著影响,职业技能竞赛对成长潜力有显著影响。培养高职学生创业能力需要进行多角度创业实践,积极参与创业竞赛,完善创业教育体系。  相似文献   

妊娠期糖尿病相关炎性因子的研究进展     

何可人  单莉莉  刘芳  王珊 《深圳职业技术学院学报》2021,(1)

目前妊娠期糖尿病的发病机制尚不完全清楚,随着研究的进展,免疫炎症假说日益受到学者的重视.妊娠期糖尿病的发病与病人体内的促炎/抗炎细胞因子平衡失常有关,该平衡倾向于促炎细胞因子的分泌,而抗炎细胞因子在疾病的发生、发展中可能发挥保护作用,文章综述了促炎细胞因子(TNF-6、IL-6、IFN-γ、IL-2、IL-17、IL-1β)和抗炎细胞因子(IL-10、IL-37、IL-4)在妊娠期糖尿病发生、发展中的作用,以及它们在临床筛查和诊断中的应用,以期为妊娠期糖尿病的预测和防治提供参考.  相似文献   

基于因子偏离度的GBDT多因子选股模型     

邓晶 《教育技术导刊》2021,20(1):109-112

为了避免股票市场中因子之间复杂非线性关系引起的多因子选股模型过拟合现象,基于因子偏离度对股票因子数据进行分析,筛选影响股票收益率的有效因子,通过梯度提升树对股票影响因子的权值进行不断调整和分析,建立一个DEV-GBDT量化选股模型,再根据基于因子偏离度的GBDT多因子选股模型的预测结果进行模拟交易,以沪深300指数成分股2010年1月1日—2019年7月31日数据为例进行实证分析。实验结果表明,DEV-GBDT选股模型的年化收益率达26.14%,比传统GBDT选股模型提高8.61%。基于因子偏离度的GBDT多因子选股模型能有效识别股市影响因子,提高股票预测准确度,帮助投资者获得超额收益。  相似文献   

CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement     

Li  Chao  Brant  Eleanor  Budak  Hikmet  Zhang  Baohong 《Journal of Zhejiang University. Science. B》2021,22(4):253-284

Since it was first recognized in bacteria and archaea as a mechanism for innate viral immunity in the early 2010 s,clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein(Cas) has rapidly been developed into a robust, multifunctional genome editing tool with many uses. Following the discovery of the initial CRISPR/Cas-based system, the technology has been advanced to facilitate a multitude of different functions. These include development as a base editor, prime editor, epigenetic editor, and CRISPR interference(CRISPRi) and CRISPR activator(CRISPRa) gene regulators. It can also be used for chromatin and RNA targeting and imaging. Its applications have proved revolutionary across numerous biological fields, especially in biomedical and agricultural improvement. As a diagnostic tool, CRISPR has been developed to aid the detection and screening of both human and plant diseases, and has even been applied during the current coronavirus disease 2019(COVID-19) pandemic. CRISPR/Cas is also being trialed as a new form of gene therapy for treating various human diseases, including cancers, and has aided drug development. In terms of agricultural breeding, precise targeting of biological pathways via CRISPR/Cas has been key to regulating molecular biosynthesis and allowing modification of proteins, starch, oil, and other functional components for crop improvement. Adding to this, CRISPR/Cas has been shown capable of significantly enhancing both plant tolerance to environmental stresses and overall crop yield via the targeting of various agronomically important gene regulators. Looking to the future, increasing the efficiency and precision of CRISPR/Cas delivery systems and limiting off-target activity are two major challenges for wider application of the technology. This review provides an in-depth overview of current CRISPR development, including the advantages and disadvantages of the technology,recent applications, and future considerations.  相似文献   

Genome-wide analysis of microRNA156 and its targets,the genes encoding SQUAMOSA promoter-binding protein-like (SPL) transcription factors,in the grass family Poaceae     

Yue  Erkui  Tao  Hua  Xu  Jianhong 《Journal of Zhejiang University. Science. B》2021,22(5):366-382

  相似文献